Linked Life Data

19841426

Source:http://linkedlifedata.com/resource/pubmed/id/19841426

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2009-10-20
pubmed:abstractText
In recent years, brain tumors have become the single most frequent cause of cancer-related mortality in children, although their frequency is approximately 50% less than leukemia. According to the classification of the World Health Organization, histopathological diagnosis is of paramount importance for clinicians to choose the most appropriate treatment option and tailor treatment intensity to disease risk. However, histopathological assessment is often difficult, and adding molecular information to classic neuropathological analyses may help ensure diagnostic accuracy, improve risk stratification of patients within a given tumor entity, and help in identifying novel therapeutic targets for an individualized treatment approach. Therefore, this review focuses both on established histopathology as well as on molecular features in the most important brain tumors in children.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1708-8283
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1375-86
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Histology and molecular pathology of pediatric brain tumors.
pubmed:affiliation
Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany. s.pfister@dkfz.de
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't