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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-11-9
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pubmed:abstractText |
Fluorescent and luminescent gene reporters allow us to dynamically quantify changes in molecular species concentration over time on the single cell level. The mathematical modeling of their interaction through multivariate dynamical models requires the development of effective statistical methods to calibrate such models against available data. Given the prevalence of stochasticity and noise in biochemical systems inference for stochastic models is of special interest. In this paper we present a simple and computationally efficient algorithm for the estimation of biochemical kinetic parameters from gene reporter data.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-12145321,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-12183631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-14559783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-14597651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-14597656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-15246787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-15499023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-16135029,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-16179466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-16224022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-17068087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-17660527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-18097413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-18573089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-18974172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-19139763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-19167290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-8526893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19840370-9927716
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2105
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
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pubmed:year |
2009
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pubmed:articleTitle |
Bayesian inference of biochemical kinetic parameters using the linear noise approximation.
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pubmed:affiliation |
Department of Statistics, University of Warwick, Coventry, UK. M.Komorowski@warwick.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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