Linked Life Data

19840363

Source:http://linkedlifedata.com/resource/pubmed/id/19840363

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-2-19
pubmed:abstractText
The interaction of glycoprotein (GP) Ibalpha with von Willebrand factor (VWF) initiates platelet adhesion, and simultaneously triggers intracellular signaling cascades leading to platelet aggregation and thrombus formation. Some of the signaling events are similar to those occurring during apoptosis, however, it is still unclear whether platelet apoptosis is induced by the GPIbalpha-VWF interaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1538-7836
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-50
pubmed:meshHeading
pubmed-meshheading:19840363-14-3-3 Proteins, pubmed-meshheading:19840363-Animals, pubmed-meshheading:19840363-Apoptosis, pubmed-meshheading:19840363-Binding Sites, pubmed-meshheading:19840363-Blood Platelets, pubmed-meshheading:19840363-CHO Cells, pubmed-meshheading:19840363-Cricetinae, pubmed-meshheading:19840363-Cricetulus, pubmed-meshheading:19840363-Gelsolin, pubmed-meshheading:19840363-Humans, pubmed-meshheading:19840363-Membrane Potential, Mitochondrial, pubmed-meshheading:19840363-Mutation, pubmed-meshheading:19840363-Phosphatidylserines, pubmed-meshheading:19840363-Platelet Activation, pubmed-meshheading:19840363-Platelet Glycoprotein GPIb-IX Complex, pubmed-meshheading:19840363-Protein Binding, pubmed-meshheading:19840363-Protein Structure, Tertiary, pubmed-meshheading:19840363-Ristocetin, pubmed-meshheading:19840363-Signal Transduction, pubmed-meshheading:19840363-Stress, Mechanical, pubmed-meshheading:19840363-Transfection, pubmed-meshheading:19840363-bcl-2 Homologous Antagonist-Killer Protein, pubmed-meshheading:19840363-bcl-2-Associated X Protein, pubmed-meshheading:19840363-von Willebrand Factor
pubmed:year
2010
pubmed:articleTitle
The glycoprotein Ibalpha-von Willebrand factor interaction induces platelet apoptosis.
pubmed:affiliation
School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't