Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-10-19
pubmed:abstractText
The fatty acid composition of serum phospholipids has been shown to reflect dietary intakes in the previous weeks or months. However, how serum phospholipids relate to fatty acid intakes over a few years has hardly been examined. We designed a cross-sectional study within the E3N cohort, the French component of the European Prospective Investigation into Cancer and Nutrition in which female participants completed a 208-item diet history questionnaire in 1993-1995 and provided blood samples in 1995-1998. The study included 1,114 women who were free of cancer at the time of blood collection. Serum phospholipid fatty acid composition was assessed by capillary gas chromatography. Partial Spearman correlations adjusted for age and body mass index showed weak to moderate, although statistically significant, positive associations between dietary and serum oleic, linoleic, arachidonic, eicosapentaenoic, and docosahexaenoic acids. Moreover, serum oleic acid was directly associated with olive oil, linoleic acid with sunflower oil, pentadecanoic acid with dairy products, long-chain n-3 fatty acids with fatty fish, and trans-monounsaturated fatty acids with manufactured foods. In conclusion, serum phospholipid pentadecanoic acid, oleic, trans-monounsaturated, and polyunsaturated fatty acids are suitable biomarkers for usual dietary intakes, although the association may weaken as the time lag between dietary assessment and blood collection increases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1532-7914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
500-9
pubmed:meshHeading
pubmed-meshheading:19838922-Adult, pubmed-meshheading:19838922-Aged, pubmed-meshheading:19838922-Aging, pubmed-meshheading:19838922-Alcohol Drinking, pubmed-meshheading:19838922-Biological Markers, pubmed-meshheading:19838922-Body Mass Index, pubmed-meshheading:19838922-Case-Control Studies, pubmed-meshheading:19838922-Cohort Studies, pubmed-meshheading:19838922-Cross-Sectional Studies, pubmed-meshheading:19838922-Diet, pubmed-meshheading:19838922-Diet Surveys, pubmed-meshheading:19838922-Dietary Fats, pubmed-meshheading:19838922-Energy Intake, pubmed-meshheading:19838922-Fatty Acids, pubmed-meshheading:19838922-Female, pubmed-meshheading:19838922-France, pubmed-meshheading:19838922-Humans, pubmed-meshheading:19838922-Menopause, pubmed-meshheading:19838922-Middle Aged, pubmed-meshheading:19838922-Phospholipids, pubmed-meshheading:19838922-Questionnaires, pubmed-meshheading:19838922-Reproducibility of Results, pubmed-meshheading:19838922-Smoking, pubmed-meshheading:19838922-Statistics, Nonparametric, pubmed-meshheading:19838922-Time Factors
pubmed:year
2009
pubmed:articleTitle
Correlation between serum phospholipid fatty acids and dietary intakes assessed a few years earlier.
pubmed:affiliation
INSERM, ERI-20, Université Paris XI, EA 4045, Institut Gustave Roussy, Villejuif, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study