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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0017337,
umls-concept:C0031437,
umls-concept:C0032460,
umls-concept:C0046725,
umls-concept:C0085862,
umls-concept:C0205419,
umls-concept:C0311400,
umls-concept:C0332307,
umls-concept:C0750484,
umls-concept:C1299583,
umls-concept:C1549571,
umls-concept:C1608386
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pubmed:issue |
12
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pubmed:dateCreated |
2009-12-4
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pubmed:abstractText |
Few candidate genes for polycystic ovary syndrome (PCOS) are widely agreed upon largely due to lack of replication. Type 6 17beta-hydroxysteroid dehydrogenase (HSD17B6) gene expression is increased in PCOS ovarian theca. Previous genetic study of HSD17B6 reported significant association of rs898611 with PCOS risk and metabolic phenotypes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1945-7197
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5034-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19837928-Adult,
pubmed-meshheading:19837928-Alleles,
pubmed-meshheading:19837928-Body Mass Index,
pubmed-meshheading:19837928-Cohort Studies,
pubmed-meshheading:19837928-European Continental Ancestry Group,
pubmed-meshheading:19837928-Female,
pubmed-meshheading:19837928-Genetic Variation,
pubmed-meshheading:19837928-Genotype,
pubmed-meshheading:19837928-Haplotypes,
pubmed-meshheading:19837928-Humans,
pubmed-meshheading:19837928-Insulin,
pubmed-meshheading:19837928-Phenotype,
pubmed-meshheading:19837928-Polycystic Ovary Syndrome,
pubmed-meshheading:19837928-Polymorphism, Single Nucleotide,
pubmed-meshheading:19837928-Racemases and Epimerases,
pubmed-meshheading:19837928-Risk,
pubmed-meshheading:19837928-Steroids
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pubmed:year |
2009
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pubmed:articleTitle |
Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene.
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pubmed:affiliation |
Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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