Linked Life Data

19836237

Source:http://linkedlifedata.com/resource/pubmed/id/19836237

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2009-11-5
pubmed:abstractText
Human MST/hSAV/LATS/hMOB tumor suppressor cascades are regulators of cell death and proliferation; however, little is known about other functions of MST/hMOB signaling. Mob1p, one of two MOB proteins in yeast, appears to play a role in spindle pole body duplication (the equivalent of mammalian centrosome duplication). We therefore investigated the role of human MOB proteins in centrosome duplication. We also addressed the regulation of human centrosome duplication by mammalian serine/threonine Ste20-like (MST) kinases, considering that MOB proteins can function together with Ste20-like kinases in eukaryotes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1879-0445
pubmed:author
pubmed:issnType
Electronic
pubmed:day
3
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1692-702
pubmed:dateRevised
2010-9-13
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation.
pubmed:affiliation
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. hergo@fmi.ch
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't