Linked Life Data

19834959

Source:http://linkedlifedata.com/resource/pubmed/id/19834959

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
24
pubmed:dateCreated
2009-12-16
pubmed:abstractText
In a recently published randomized trial, Andersen et al. claimed to observe a reduced risk of recurrence and improved survival among women with early stage breast cancer who were assigned to a psychological intervention versus an assessment-only group. Anderson et al. concluded that "psychological intervention, as delivered and studied here, can improve survival." The current commentary challenges that conclusion on methodological and statistical grounds, noting that the study by Andersen et al. was not designed to assess survival and used methods that capitalized on chance, making it highly unlikely that their claims could be replicated. No other study designed to assess whether psychosocial intervention provides a survival benefit for cancer patients has ever demonstrated such an effect; and, currently, there is no support for the hypothesis that survival benefits can be attributed to psychosocial intervention. The authors of this commentary argue that much needs to be learned at the more basic biobehavioral level about the impact of stress or psychological factors on tumor biology before even considering whether large clinical trials are warranted. In addition, making the claim that psychological interventions improve survival is not evidence-based, is potentially harmful, and detracts from the potential significant benefits of psychological interventions related to quality of life.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-543X
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 American Cancer Society.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5612-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Finding what is not there: unwarranted claims of an effect of psychosocial intervention on recurrence and survival.
pubmed:affiliation
American Cancer Society, Behavioral Research Center, Atlanta, Georgia 30303, USA. mstefanek@bellsouth.net
pubmed:publicationType
Journal Article, Comment