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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
Selective IgA deficiency (IgAD; serum IgA concentration of <0.07 g/l) is the most common primary immunodeficiency in Caucasians with an estimated prevalence of 1/600. The frequency of the extended major histocompatibility complex haplotype HLA A1, B8, DR3, DQ2 (the "8.1" haplotype) is increased among patients with IgAD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1573-2592
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
138-43
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pubmed:meshHeading |
pubmed-meshheading:19834793-Computer Simulation,
pubmed-meshheading:19834793-DNA Mutational Analysis,
pubmed-meshheading:19834793-European Continental Ancestry Group,
pubmed-meshheading:19834793-Gene Frequency,
pubmed-meshheading:19834793-Genetic Heterogeneity,
pubmed-meshheading:19834793-Genetics, Population,
pubmed-meshheading:19834793-HLA-A1 Antigen,
pubmed-meshheading:19834793-HLA-B8 Antigen,
pubmed-meshheading:19834793-HLA-DR3 Antigen,
pubmed-meshheading:19834793-Haplotypes,
pubmed-meshheading:19834793-Humans,
pubmed-meshheading:19834793-IgA Deficiency,
pubmed-meshheading:19834793-Immunoglobulin A,
pubmed-meshheading:19834793-Prevalence,
pubmed-meshheading:19834793-Risk,
pubmed-meshheading:19834793-Sample Size,
pubmed-meshheading:19834793-Sweden
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pubmed:year |
2010
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pubmed:articleTitle |
IgA deficiency and the MHC: assessment of relative risk and microheterogeneity within the HLA A1 B8, DR3 (8.1) haplotype.
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pubmed:affiliation |
Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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