Linked Life Data

1983154

Source:http://linkedlifedata.com/resource/pubmed/id/1983154

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1991-8-27
pubmed:abstractText
Myrcene, a monoterpene isolated from lemon grass oil (Cymbopogon citratus) has been investigated for antinociception in mice by a low temperature (51.5 +/- 0.5 degrees C) hot plate method and by the acetic acid-induced writhing test. Significant inhibition of nociception was seen in the tests with myrcene at doses of 10 and 20 mg kg-1 (i.p.) or at 20 and 40 mg kg-1 (s.c.), respectively. The antinociceptive effect was significantly antagonized by naloxone (1 mg kg-1) or yohimbine (2 mg kg-1). The results suggest that myrcene is capable of inducing antinociception in mice, probably mediated by alpha 2-adrenoceptor stimulated release of endogenous opioids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-3573
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
877-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Effect of myrcene on nociception in mice.
pubmed:affiliation
Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.
pubmed:publicationType
Journal Article