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pubmed-article:1982987pubmed:abstractTextAs an approach to estimate the involvement of the insulin receptor gene in the etiopathogenesis of type-II diabetes mellitus we determined the distribution of the alleles of a restriction fragment length polymorphism of this gene (Bgl II-RFLP) in a group of type-II diabetics. The patients had been characterized by insulin and C-peptide values during OGTT and insulin receptor binding indices. The difference in allelic distribution to a healthy control group (10% "+"-allele in diabetics versus 18% in control persons), was not significant in chi 2-analysis.lld:pubmed
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pubmed-article:1982987pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:1982987pubmed:articleTitleBgl II-restriction fragment length polymorphism of the insulin receptor gene in patients with type-II diabetes mellitus.lld:pubmed
pubmed-article:1982987pubmed:affiliationInstitute of Biochemistry, School of Medicine, Ernst Moritz Arndt University, Greifswald, FRG.lld:pubmed
pubmed-article:1982987pubmed:publicationTypeJournal Articlelld:pubmed