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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
12
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pubmed:dateCreated |
1991-7-25
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pubmed:abstractText |
As an approach to estimate the involvement of the insulin receptor gene in the etiopathogenesis of type-II diabetes mellitus we determined the distribution of the alleles of a restriction fragment length polymorphism of this gene (Bgl II-RFLP) in a group of type-II diabetics. The patients had been characterized by insulin and C-peptide values during OGTT and insulin receptor binding indices. The difference in allelic distribution to a healthy control group (10% "+"-allele in diabetics versus 18% in control persons), was not significant in chi 2-analysis.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0232-766X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1233-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1982987-Alleles,
pubmed-meshheading:1982987-Bacterial Proteins,
pubmed-meshheading:1982987-DNA Probes,
pubmed-meshheading:1982987-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:1982987-Diabetes Mellitus, Type 2,
pubmed-meshheading:1982987-Genotype,
pubmed-meshheading:1982987-Humans,
pubmed-meshheading:1982987-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1982987-Receptor, Insulin
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
Bgl II-restriction fragment length polymorphism of the insulin receptor gene in patients with type-II diabetes mellitus.
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pubmed:affiliation |
Institute of Biochemistry, School of Medicine, Ernst Moritz Arndt University, Greifswald, FRG.
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pubmed:publicationType |
Journal Article
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