Linked Life Data

19824424

Source:http://linkedlifedata.com/resource/pubmed/id/19824424

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-10-14
pubmed:abstractText
Statin therapy reduces blood cholesterol and lipids and exerts an anti-inflammatory effect. Certain statins bind adhesion molecules, including functional leukocytic antigen-1, and therefore block their interaction with T lymphocytes and macrophages expressing the counter-receptor intercellular adhesion molecule-1 (ICAM-1). Quantitation of endothelium-adherent T cells and macrophages revealed much smaller numbers of these cells in patients receiving statins. The authors consider that the lower count of T lymphocytes and macrophages in the upper layers of the intima and atherosclerotic plaques may facilitate the conversion of unstable to stable plaques, which reduces the risk of atherosclerotic plaque rupture and resultant vascular thrombosis.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-1955
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
23-6
pubmed:meshHeading
pubmed:articleTitle
[Anti-inflammatory properties of statins in the study of atherosclerotic plaques in the endartectomized coronary arteries].
pubmed:publicationType
Journal Article, English Abstract