Linked Life Data

1982284

Source:http://linkedlifedata.com/resource/pubmed/id/1982284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-5-22
pubmed:abstractText
Reports of abnormalities of regional cerebral blood flow (rCBF) in patients with schizophrenia and major affective disorder are contradictory. To gain a better understanding of the possible sources of these contradictions, the rCBF and neuropsychological functioning of 15 schizophrenics, 15 patients with major affective disorder, and 15 age-matched controls were studied. No group differences in overall rCBF, percent frontal deviation in flow, or rCBF asymmetries were observed. Both overall rCBF and percent frontal deviation of rCBF were reduced with greater age and with increasing neuropsychological impairment. Dosage of neuroleptic medication was associated with reduced whole brain flow, not with percent frontal deviation flow. Previously reported differences in the resting rCBF of schizophrenics might be more closely related to the age of the subjects and to their neuropsychological impairment rather than the inherent progression of the disorder.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0018-0416
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
202-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Effects of age, neuropsychological impairment, and medication on regional cerebral blood flow in schizophrenia and major affective disorder.
pubmed:affiliation
Division of Neuropsychology, Henry Ford Hospital, Detroit, MI 48202.
pubmed:publicationType
Journal Article, Comparative Study