19822779

Source:http://linkedlifedata.com/resource/pubmed/id/19822779

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011164, umls-concept:C0018591, umls-concept:C0332461, umls-concept:C0751254, umls-concept:C1100714
pubmed:issue	10
pubmed:dateCreated	2009-10-13
pubmed:abstractText	Dominantly inherited Creutzfeldt-Jakob disease (CJD) represents 5% to 15% of all CJD cases. The E200K mutation in the prion protein (PrP) gene (PRNP) is the most frequent cause of familial CJD. Coexistent amyloid beta (Abeta) plaques have been reported in some transmissible spongiform encephalopathies but to date have not been reported in familial CJD with the E200K mutation.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P01 AG003991-26, http://linkedlifedata.com/resource/pubmed/grant/P01 AG014359-13, http://linkedlifedata.com/resource/pubmed/grant/P01 AG03991, http://linkedlifedata.com/resource/pubmed/grant/P01 AG14359, http://linkedlifedata.com/resource/pubmed/grant/P50 AG005681-26, http://linkedlifedata.com/resource/pubmed/grant/P50 AG05681, http://linkedlifedata.com/resource/pubmed/grant/T32 NS007205, http://linkedlifedata.com/resource/pubmed/grant/T32 NS007205-28, http://linkedlifedata.com/resource/pubmed/grant/UR8/CCU515004
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372436
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E, http://linkedlifedata.com/resource/pubmed/chemical/Endopeptidase K, http://linkedlifedata.com/resource/pubmed/chemical/PRNP protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Prions
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1538-3687
pubmed:author	pubmed-author:CaliIgnazioI, pubmed-author:GambettiPierluigiP, pubmed-author:GhoshalNupurN, pubmed-author:JosephsonS AndrewSA, pubmed-author:MorrisJohn CarlJC, pubmed-author:PerrinRichard JustinRJ, pubmed-author:SunNingN
pubmed:issnType	Electronic
pubmed:volume	66
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1240-6
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:19822779-Age of Onset, pubmed-meshheading:19822779-Aged, 80 and over, pubmed-meshheading:19822779-Alzheimer Disease, pubmed-meshheading:19822779-Apolipoproteins E, pubmed-meshheading:19822779-Blotting, Western, pubmed-meshheading:19822779-Brain, pubmed-meshheading:19822779-Creutzfeldt-Jakob Syndrome, pubmed-meshheading:19822779-Endopeptidase K, pubmed-meshheading:19822779-Female, pubmed-meshheading:19822779-Genotype, pubmed-meshheading:19822779-Haplotypes, pubmed-meshheading:19822779-Humans, pubmed-meshheading:19822779-Immunohistochemistry, pubmed-meshheading:19822779-Male, pubmed-meshheading:19822779-Middle Aged, pubmed-meshheading:19822779-Nerve Degeneration, pubmed-meshheading:19822779-Pedigree, pubmed-meshheading:19822779-Plaque, Amyloid, pubmed-meshheading:19822779-Prions
pubmed:year	2009
pubmed:articleTitle	Codistribution of amyloid beta plaques and spongiform degeneration in familial Creutzfeldt-Jakob disease with the E200K-129M haplotype.
pubmed:affiliation	Department of Neurology and Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Ave, Ste 101, St Louis, MO 63108, USA. ghoshaln@neuro.wustl.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural