Source:http://linkedlifedata.com/resource/pubmed/id/19820429
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-6-23
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pubmed:abstractText |
In type 1 diabetes, individual susceptibility to severe hypoglycaemia is likely to be influenced by genetic factors. We have previously reported an association of the deletion (D-) allele of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the A-allele of the angiotensin II receptor subtype 2 (AT2R) 1675 G>A polymorphism with risk of severe hypoglycaemia in such patients. The aim of this study was to test the hypothesis that these alleles are more frequent in patients suffering from the most severe episodes of hypoglycaemia requiring medical emergency treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1744-6880
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
864-8
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pubmed:meshHeading |
pubmed-meshheading:19820429-Case-Control Studies,
pubmed-meshheading:19820429-Cohort Studies,
pubmed-meshheading:19820429-Diabetes Mellitus, Type 1,
pubmed-meshheading:19820429-Emergency Treatment,
pubmed-meshheading:19820429-Female,
pubmed-meshheading:19820429-Gene Frequency,
pubmed-meshheading:19820429-Genetic Predisposition to Disease,
pubmed-meshheading:19820429-Humans,
pubmed-meshheading:19820429-Hypoglycemia,
pubmed-meshheading:19820429-Male,
pubmed-meshheading:19820429-Middle Aged,
pubmed-meshheading:19820429-Multivariate Analysis,
pubmed-meshheading:19820429-Peptidyl-Dipeptidase A,
pubmed-meshheading:19820429-Receptor, Angiotensin, Type 2
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pubmed:year |
2009
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pubmed:articleTitle |
Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study.
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pubmed:affiliation |
Endocrinology Section, Department of Cardiology and Endocrinology, Hillerød Hospital, Hillerød, Denmark. ulpebj@noh.regionh.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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