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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1991-5-8
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pubmed:abstractText |
The sulfur-containing 3-alkylaminochromans, 5-methoxy-3-[N-(2- methylthioethyl)-propylamino]chroman (15), 5-hydroxy-3-[N-(2-methylthioethyl)propylamino]chroman (5) and 5-methoxy-8-methylthio-3-(dipropylamino)chroman (6), have been prepared from 8-bromo-5-methoxy-3-chromanol (11). This precursor was synthesized from 3-allyloxy-4-bromoanisole (8), by a thallium(III)-mediated ring-closure reaction. Compound 11 also served as starting material for the synthesis of 8-bromo-3-(dipropylamino)-5-methoxychroman (7).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0904-213X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1024-8
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:1981973-Chromans,
pubmed-meshheading:1981973-Cyclization,
pubmed-meshheading:1981973-Dopamine Agents,
pubmed-meshheading:1981973-Molecular Structure,
pubmed-meshheading:1981973-Receptors, Serotonin,
pubmed-meshheading:1981973-Structure-Activity Relationship,
pubmed-meshheading:1981973-Thallium
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pubmed:year |
1990
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pubmed:articleTitle |
Synthesis of 3-dialkylaminochromans via thallium(III)-induced cyclization of allyl aryl ethers.
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pubmed:affiliation |
Department of Pharmacology, University of Göteborg, Sweden.
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pubmed:publicationType |
Journal Article
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