This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and MCF-7 and compared to Photofrin II.
Université de Limoges, Laboratoire de Chimie des Substances Naturelles EA 1069, Faculté des Sciences et Techniques, 123 Av. Albert Thomas, 87060 Limoges, France.