Source:http://linkedlifedata.com/resource/pubmed/id/19818997
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-12-7
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pubmed:abstractText |
Androgen signaling may function in the pathobiology of epithelial ovarian cancers associated with mutations in the BRCA1/2 genes. Androgen receptor (AR) activity correlates inversely with length of a polymorphic cytosine-adenine-guanine (CAG) repeat in exon 1. We hypothesized that AR CAG allele length is a modifier of clinical outcome in BRCA1/2 mutation positive women with ovarian cancer.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1095-6859
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-8
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pubmed:meshHeading |
pubmed-meshheading:19818997-Alleles,
pubmed-meshheading:19818997-Epithelial Cells,
pubmed-meshheading:19818997-Female,
pubmed-meshheading:19818997-Genes, BRCA1,
pubmed-meshheading:19818997-Genes, BRCA2,
pubmed-meshheading:19818997-Genotype,
pubmed-meshheading:19818997-Germ-Line Mutation,
pubmed-meshheading:19818997-Humans,
pubmed-meshheading:19818997-Middle Aged,
pubmed-meshheading:19818997-Neoplasm Staging,
pubmed-meshheading:19818997-Ovarian Neoplasms,
pubmed-meshheading:19818997-Receptors, Androgen,
pubmed-meshheading:19818997-Repetitive Sequences, Nucleic Acid
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pubmed:year |
2010
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pubmed:articleTitle |
Impact of androgen receptor cytosine-adenine-guanine polymorphisms on clinical outcome in BRCA mutation-associated epithelial ovarian cancers.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Suite 160W, Los Angeles, CA 90048, USA. Andrew.Li@cshs.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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