Linked Life Data

1981675

Source:http://linkedlifedata.com/resource/pubmed/id/1981675

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1991-4-24
pubmed:abstractText
A major portion of airway blood flow is distributed to the subepithelial tissue space and is strategically located to influence both epithelial and airway smooth muscle functions. To assess the magnitude and responsiveness of blood flow through the subepithelial microvasculature, we measured tracheal mucosal blood flow with a soluble gas method in intact sheep. We found responses of tracheal mucosal blood flow to pharmacological stimuli alpha- and beta- (adrenoceptor agonists) and inflammatory stimuli (antigen and histamine), and demonstrated that alterations in mucosal blood flow influence the magnitude and duration of allergic airway smooth muscle contraction in the trachea. Mucosal blood flow, which under certain circumstances is regulated independently of total airway blood flow, could play a critical role in the manifestations of and recovery from airway disease.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0904-1850
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
618s-623s
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Airway mucosal blood flow: response to autonomic and inflammatory stimuli.
pubmed:affiliation
Division of Pulmonary Disease, University of Miami, Mount Sinai Medical Center, Florida 33140.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't