Source:http://linkedlifedata.com/resource/pubmed/id/19815658
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-1-20
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pubmed:abstractText |
The inhibitor of kB kinase (IKK) complex, a critical positive regulator of nuclear factor kappaB (NF-kappaB) signaling and immune function, can be activated in vitro by polyubiquitin chains. The modification of signaling intermediates by polyubiquitin and their association with ubiquitin-binding domain-containing proteins within multimolecular signaling complexes therefore represent a potential mechanism for activation of IKK and NF-kappaB in vivo.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1759-4685
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-2
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pubmed:dateRevised |
2010-12-21
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Direct activation of protein kinases by ubiquitin.
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pubmed:affiliation |
Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
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pubmed:publicationType |
Journal Article
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