Linked Life Data

1981435

Source:http://linkedlifedata.com/resource/pubmed/id/1981435

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-4-11
pubmed:abstractText
The effects of tetracycline, minocycline and erythromycin on complement activation in vitro were studied. At concentrations of 100 mg/l or less, these antibiotics did not inhibit the capacity of Propionibacterium acnes to cleave C3 in normal human serum or in serum chelated of Ca2+ allowing complement activation by the alternative pathway alone. The antibiotics had no effect (at 100 mg/l) on total haemolytic activity of complement in normal human serum. This study did not provide evidence to support the hypothesis that the efficacy of these antibiotics in the therapy of inflammatory acne vulgaris can be explained by inhibition of complement activation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5555
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
531-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
The effects of tetracyclines and erythromycin on complement activation in vitro.
pubmed:affiliation
Department of Immunology, University of Leeds, W. Yorkshire, England.
pubmed:publicationType
Journal Article, In Vitro