Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2010-1-21
pubmed:abstractText
Neoadjuvant therapy is now an integral part in the treatment of locally advanced cancer of the esophagus and stomach. The mechanisms of action comprise downsizing of the primary tumor, improvement of the T and N categories and the earliest possible eradication of micrometastases. Several controlled clinical studies could show that these principles can indeed augment the rate of curative (R0) resections and can reduce the likelihood of systemic recurrences. As a consequence overall survival is improved by neoadjuvant therapy. This article summarizes how the basic principles of neoadjuvant therapy translate into clinical practice and gives a review of current developmental perspectives in this field.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1433-0385
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1000-5
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[Principles of neoadjuvant therapy].
pubmed:affiliation
Medizinische Klinik III, Innere Medizin, Hämatologie und Onkologie, Klinikum Braunschweig, Celler Strasse 38, 38114, Braunschweig, Deutschland. medklinik3@klinikum-braunschweig.de
pubmed:publicationType
Journal Article, English Abstract, Review