rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2010-2-25
|
pubmed:abstractText |
Pancreatic carcinoma etiology and molecular pathogenesis are weakly understood. Based on the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, we studied the association of polymorphisms in the tobacco carcinogen-metabolizing gene CYP2A13 (Arg101Stop) and the alcohol-metabolizing genes ADH1B (Arg48His) and ADH1C (Ile350Val) with pancreatic cancer risk.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
1536-4828
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
144-8
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pubmed:meshHeading |
pubmed-meshheading:19812523-Aged,
pubmed-meshheading:19812523-Alcohol Dehydrogenase,
pubmed-meshheading:19812523-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:19812523-Carcinoma,
pubmed-meshheading:19812523-Case-Control Studies,
pubmed-meshheading:19812523-Female,
pubmed-meshheading:19812523-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19812523-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19812523-Gene Frequency,
pubmed-meshheading:19812523-Genetic Predisposition to Disease,
pubmed-meshheading:19812523-Hospitals,
pubmed-meshheading:19812523-Humans,
pubmed-meshheading:19812523-Logistic Models,
pubmed-meshheading:19812523-Male,
pubmed-meshheading:19812523-Middle Aged,
pubmed-meshheading:19812523-Odds Ratio,
pubmed-meshheading:19812523-Pancreatic Neoplasms,
pubmed-meshheading:19812523-Polymorphism, Genetic,
pubmed-meshheading:19812523-Risk Assessment,
pubmed-meshheading:19812523-Risk Factors
|
pubmed:year |
2010
|
pubmed:articleTitle |
CYP2A13, ADH1B, and ADH1C gene polymorphisms and pancreatic cancer risk.
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pubmed:affiliation |
Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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