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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-3-25
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pubmed:abstractText |
The mouse chromosomal location for the gene (Sp1-1) encoding the trans-acting transcription factor Sp1 has been determined. Analysis of restriction fragment length polymorphisms in recombinant inbred, congenic, and interspecific backcross mice using human and mouse cDNA probes demonstrated that Sp1-1 is a single gene closely linked to the mammary tumor virus integration site-1 (Int-1) on the distal end of chromosome 15. Sp1 is a zinc finger protein, but Sp1-1 is not closely linked to any of the other zinc finger protein genes that have been mapped in mouse. Int-1 and other markers flanking the Sp1-1 locus are part of a conserved linkage group represented on human chromosome 12q.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:geneSymbol |
Gdc-1,
Sp1-1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
571-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:1981055-Animals,
pubmed-meshheading:1981055-Chromosome Mapping,
pubmed-meshheading:1981055-Crosses, Genetic,
pubmed-meshheading:1981055-DNA,
pubmed-meshheading:1981055-Female,
pubmed-meshheading:1981055-Genes,
pubmed-meshheading:1981055-Genetic Linkage,
pubmed-meshheading:1981055-Genetic Markers,
pubmed-meshheading:1981055-Humans,
pubmed-meshheading:1981055-Male,
pubmed-meshheading:1981055-Mice,
pubmed-meshheading:1981055-Mice, Inbred Strains,
pubmed-meshheading:1981055-Muridae,
pubmed-meshheading:1981055-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1981055-Recombination, Genetic,
pubmed-meshheading:1981055-Sp1 Transcription Factor,
pubmed-meshheading:1981055-Species Specificity,
pubmed-meshheading:1981055-Zinc Fingers
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pubmed:year |
1990
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pubmed:articleTitle |
Localization of the gene for the trans-acting transcription factor Sp1 to the distal end of mouse chromosome 15.
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pubmed:affiliation |
Jackson Laboratory, Bar Harbor, Maine 04609.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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