rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-10-7
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pubmed:abstractText |
Methylated arginines are endogenous analogues of L-arginine, the substrate for nitric oxide (NO) synthase. Asymmetric dimethylarginine (ADMA) interferes with NO formation, causing endothelial dysfunction. ADMA is a predictor of cardiovascular events and mortality in humans. It is eliminated primarily by enzymatic activity of dimethylarginine dimethylaminohydrolase (DDAH).
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-12805079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-14638548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-15781754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-16055131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-16581698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-16809568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-17317881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-17349891,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-17559823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-18063827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-19265055,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-19289633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809508-7503244
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
4
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e7337
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pubmed:meshHeading |
pubmed-meshheading:19809508-Amidohydrolases,
pubmed-meshheading:19809508-Animals,
pubmed-meshheading:19809508-Arginine,
pubmed-meshheading:19809508-Brain,
pubmed-meshheading:19809508-Endothelium, Vascular,
pubmed-meshheading:19809508-Genotype,
pubmed-meshheading:19809508-Infarction, Middle Cerebral Artery,
pubmed-meshheading:19809508-Ischemia,
pubmed-meshheading:19809508-Male,
pubmed-meshheading:19809508-Mice,
pubmed-meshheading:19809508-Mice, Transgenic,
pubmed-meshheading:19809508-Models, Biological,
pubmed-meshheading:19809508-Nitric Oxide,
pubmed-meshheading:19809508-Stroke
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pubmed:year |
2009
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pubmed:articleTitle |
Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.
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pubmed:affiliation |
Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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