|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2009-10-7
|
|
pubmed:abstractText |
Carriage of Neisseria meningitidis occurs approximately in 10% of the population, onset of invasive meningococcal disease (IMD) cannot be predicted and differs between ages. It remains unclear, which host factors determine invasion of the bloodstream by the bacteria. Innate immunity has a very important role in the first recognition of invading pathogens. The functional single nucleotide polymorphisms (SNPs) CD14 C-159T and toll-like receptor 4 (TLR4) Asp299Gly have been associated with the risk of gram-negative infections. However, their role in development of IMD still remains unclear. Our aim was to investigate the influence of CD14 C-159T and TLR4 Asp299Gly polymorphisms on the risk of IMD.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-10226067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-10385492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-11179155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-11494169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-11698458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-12404174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-12580907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-12730365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-12954563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-15175649,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-15753758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-16238823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-16395111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-1698311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-17021322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-17877801,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-18679149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-19242354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-7534618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-7690322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19809507-8811052
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
4
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e7374
|
|
pubmed:meshHeading |
pubmed-meshheading:19809507-Adolescent,
pubmed-meshheading:19809507-Adult,
pubmed-meshheading:19809507-Aged,
pubmed-meshheading:19809507-Antigens, CD14,
pubmed-meshheading:19809507-Case-Control Studies,
pubmed-meshheading:19809507-Child,
pubmed-meshheading:19809507-Child, Preschool,
pubmed-meshheading:19809507-Female,
pubmed-meshheading:19809507-Genotype,
pubmed-meshheading:19809507-Humans,
pubmed-meshheading:19809507-Immunity, Innate,
pubmed-meshheading:19809507-Infant,
pubmed-meshheading:19809507-Male,
pubmed-meshheading:19809507-Meningococcal Infections,
pubmed-meshheading:19809507-Middle Aged,
pubmed-meshheading:19809507-Odds Ratio,
pubmed-meshheading:19809507-Polymorphism, Genetic,
pubmed-meshheading:19809507-Polymorphism, Single Nucleotide,
pubmed-meshheading:19809507-Retrospective Studies,
pubmed-meshheading:19809507-Risk,
pubmed-meshheading:19809507-Toll-Like Receptor 4
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
CD14 C-159T and toll-like receptor 4 Asp299Gly polymorphisms in surviving meningococcal disease patients.
|
|
pubmed:affiliation |
Department of Pediatrics, University Teaching Hospital, Feldkirch, Austria. ariane.biebl@gespag.at
|
|
pubmed:publicationType |
Journal Article
|
