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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-10-7
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pubmed:abstractText |
The urocortins are emerging as potentially important contributors to neurohumoral regulation of the circulation with recent reports attributing a powerful array of hemodynamic, renal, and neurohumoral effects to the urocortins in cardiac failure. These peptides also seem to have cardioprotective effects in the setting of ischemia-reperfusion. Little is known concerning the plasma concentrations of the urocortins in health and disease. We have investigated plasma urocortin 1 as a potential diagnostic marker of heart failure and documented its relationships to symptoms, measures of cardiac function, and concurrent levels of other circulating neurohormones.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1941-3297
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
465-71
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pubmed:meshHeading |
pubmed-meshheading:19808377-Adrenomedullin,
pubmed-meshheading:19808377-Adult,
pubmed-meshheading:19808377-Aged,
pubmed-meshheading:19808377-Aged, 80 and over,
pubmed-meshheading:19808377-Biological Markers,
pubmed-meshheading:19808377-Creatinine,
pubmed-meshheading:19808377-Endothelin-1,
pubmed-meshheading:19808377-Female,
pubmed-meshheading:19808377-Heart Failure,
pubmed-meshheading:19808377-Humans,
pubmed-meshheading:19808377-Logistic Models,
pubmed-meshheading:19808377-Male,
pubmed-meshheading:19808377-Middle Aged,
pubmed-meshheading:19808377-Natriuretic Peptides,
pubmed-meshheading:19808377-Predictive Value of Tests,
pubmed-meshheading:19808377-Prospective Studies,
pubmed-meshheading:19808377-ROC Curve,
pubmed-meshheading:19808377-Severity of Illness Index,
pubmed-meshheading:19808377-Up-Regulation,
pubmed-meshheading:19808377-Urocortins,
pubmed-meshheading:19808377-Ventricular Function, Left
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pubmed:year |
2009
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pubmed:articleTitle |
Plasma urocortin 1 in human heart failure.
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pubmed:affiliation |
Department of Medicine, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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