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rdf:type |
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lifeskim:mentions |
umls-concept:C0087111,
umls-concept:C0183683,
umls-concept:C0344211,
umls-concept:C0443254,
umls-concept:C0497231,
umls-concept:C1135361,
umls-concept:C1171411,
umls-concept:C1317973,
umls-concept:C1418424,
umls-concept:C1521721,
umls-concept:C1999216
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pubmed:issue |
4
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pubmed:dateCreated |
2009-10-7
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pubmed:abstractText |
Pulmonary hypertension (PH) secondary to left heart failure portends a poor prognosis and is a relative contraindication to heart transplantation at many centers. We tested the hypothesis that when PH persists after adequate left ventricle unloading via recent left ventricular assist device (LVAD) therapy, phosphodiesterase type 5A inhibition would decrease PH in this population.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1941-3297
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pubmed:author |
pubmed-author:ChampionHunter CHC,
pubmed-author:ConteJohn VJV,
pubmed-author:GirgisReda ERE,
pubmed-author:HassounPaul MPM,
pubmed-author:HemnesAnna RAR,
pubmed-author:MahmudMobusherM,
pubmed-author:MathaiStephen CSC,
pubmed-author:OrensJonathan BJB,
pubmed-author:RussellStuart DSD,
pubmed-author:ShahAshish SAS,
pubmed-author:TedfordRyan JRJ,
pubmed-author:ThiemannDavid RDR,
pubmed-author:WittsteinIlan SIS,
pubmed-author:YuhDavidD,
pubmed-author:ZaimanAri LAL
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pubmed:issnType |
Electronic
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-9
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pubmed:dateRevised |
2011-1-10
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pubmed:meshHeading |
pubmed-meshheading:19808294-Adult,
pubmed-meshheading:19808294-Female,
pubmed-meshheading:19808294-Heart-Assist Devices,
pubmed-meshheading:19808294-Hemodynamics,
pubmed-meshheading:19808294-Humans,
pubmed-meshheading:19808294-Hypertension, Pulmonary,
pubmed-meshheading:19808294-Male,
pubmed-meshheading:19808294-Middle Aged,
pubmed-meshheading:19808294-Phosphodiesterase 5 Inhibitors,
pubmed-meshheading:19808294-Phosphodiesterase Inhibitors,
pubmed-meshheading:19808294-Treatment Outcome,
pubmed-meshheading:19808294-Vascular Resistance,
pubmed-meshheading:19808294-Ventricular Dysfunction, Left
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pubmed:year |
2008
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pubmed:articleTitle |
PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support.
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pubmed:affiliation |
Divisions of Cardiology and Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkins Medical Institutions, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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