| pubmed-article:19806792 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19806792 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:19806792 | lifeskim:mentions | umls-concept:C0699791 | lld:lifeskim |
| pubmed-article:19806792 | lifeskim:mentions | umls-concept:C1518174 | lld:lifeskim |
| pubmed-article:19806792 | lifeskim:mentions | umls-concept:C0018270 | lld:lifeskim |
| pubmed-article:19806792 | pubmed:issue | 11-12 | lld:pubmed |
| pubmed-article:19806792 | pubmed:dateCreated | 2009-10-7 | lld:pubmed |
| pubmed-article:19806792 | pubmed:abstractText | The effect of B cell-specific MLV integration site-1 (Bmi-1) RNA interference (RNAi)-mediated inhibition of Bmi-1 expression on the proliferation, apoptosis, and invasiveness of human gastric carcinoma AGS cells was investigated. RT-PCR and Western blot analyses demonstrated that Bmi-1 expression and the Bmi-1 protein level were significantly decreased in Bmi-1 shRNA transfected AGS cells compared to untransfected and nonspecific shRNA transfected AGS cells. Bmi-1 RNAi-mediated inhibition of Bmi-1 expression significantly affected cell growth and invasiveness, and resulted in increased AGS cell apoptosis. This was not observed in untransfected and nonspecific shRNA transfected AGS cells. Inhibition of Bmi-1 expression in human gastric carcinoma cells affects cell proliferation and invasiveness. | lld:pubmed |
| pubmed-article:19806792 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19806792 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19806792 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19806792 | pubmed:issn | 0965-0407 | lld:pubmed |
| pubmed-article:19806792 | pubmed:author | pubmed-author:DengChangshen... | lld:pubmed |
| pubmed-article:19806792 | pubmed:author | pubmed-author:XiaoJunJ | lld:pubmed |
| pubmed-article:19806792 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19806792 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:19806792 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19806792 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19806792 | pubmed:pagination | 613-20 | lld:pubmed |
| pubmed-article:19806792 | pubmed:meshHeading | pubmed-meshheading:19806792... | lld:pubmed |
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| pubmed-article:19806792 | pubmed:meshHeading | pubmed-meshheading:19806792... | lld:pubmed |
| pubmed-article:19806792 | pubmed:meshHeading | pubmed-meshheading:19806792... | lld:pubmed |
| pubmed-article:19806792 | pubmed:meshHeading | pubmed-meshheading:19806792... | lld:pubmed |
| pubmed-article:19806792 | pubmed:meshHeading | pubmed-meshheading:19806792... | lld:pubmed |
| pubmed-article:19806792 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19806792 | pubmed:articleTitle | Knockdown of Bmi-1 impairs growth and invasiveness of human gastric carcinoma cells. | lld:pubmed |
| pubmed-article:19806792 | pubmed:affiliation | Department of Gastroenterology and Hubei Provincial Center of Clinical Study for Digestive Diseases, Zhongnan Hospital, the Key Laboratory of Allergy and Immune-related Diseases, Wuhan University School of Medicine, Wuhan, PR China. xiaojunzhongnan@163.com | lld:pubmed |
| pubmed-article:19806792 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:648 | entrezgene:pubmed | pubmed-article:19806792 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19806792 | lld:entrezgene |
