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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
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|
pubmed:dateCreated |
1991-3-6
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|
pubmed:abstractText |
The primary sequence of trypsin inhibitor-2 (WBTI-2) from Psophocarpus tetragonolobus (L.) DC seeds was determined. This inhibitor consists of a single polypeptide chain of 182 amino acids, including four half-cystine residues, and an N-terminal residue of pyroglutamic acid. The sequence of WBTI-2 showed 57% identity to the basic trypsin inhibitor (WBTI-3) and 50% identity to the chymotrypsin inhibitor (WBCI) of winged bean, and 54% identity to the trypsin inhibitor DE-3 from Erythrina latissima seed. The similarity to the soybean Kunitz trypsin inhibitor (40%) and the other Kunitz-type inhibitors from Adenanthera pavonina (30%) and wheat (26%) was much lower. Sequence comparisons indicate that the Psophocarpus and Erythrina inhibitors are more closely related to each other than to other members of the Kunitz inhibitor family.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Aug
|
|
pubmed:issn |
0277-8033
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
493-9
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1980416-Amino Acid Sequence,
pubmed-meshheading:1980416-Chymotrypsin,
pubmed-meshheading:1980416-Cysteine Endopeptidases,
pubmed-meshheading:1980416-Fabaceae,
pubmed-meshheading:1980416-Molecular Sequence Data,
pubmed-meshheading:1980416-Peptide Fragments,
pubmed-meshheading:1980416-Plant Proteins,
pubmed-meshheading:1980416-Plants, Medicinal,
pubmed-meshheading:1980416-Pyroglutamyl-Peptidase I,
pubmed-meshheading:1980416-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1980416-Trypsin,
pubmed-meshheading:1980416-Trypsin Inhibitors
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
Amino acid sequence of the acidic Kunitz-type trypsin inhibitor from winged-bean seed [Psophocarpus tetragonolobus (L.) DC].
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pubmed:affiliation |
CSIRO, Division of Biotechnology, Parkville Laboratory, Victoria, Australia.
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pubmed:publicationType |
Journal Article,
Comparative Study
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