Source:http://linkedlifedata.com/resource/pubmed/id/19798642
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-10-14
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pubmed:abstractText |
Neuromyelitis optica (NMO) is presumably mediated by an autoantibody against aquaporin-4 densely expressed at the blood-brain barrier. In 18 patients with NMO, brain magnetic resonance imaging (MRI) findings were systematically reviewed. Brain MRI abnormalities were found for 89% of the patients, and the most prominent feature was "cloud-like enhancement," multiple patchy enhancing lesions with blurred margin, found in 90% of the patients with positive contrast enhancement. In NMO, brain MRI abnormalities are frequent, and cloud-like enhancement appears to be an MRI finding specific to NMO, possibly caused by primary involvement of the blood-brain barrier by the autoantibodies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1531-8249
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
425-8
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pubmed:meshHeading |
pubmed-meshheading:19798642-Adult,
pubmed-meshheading:19798642-Aquaporin 4,
pubmed-meshheading:19798642-Autoantibodies,
pubmed-meshheading:19798642-Blood-Brain Barrier,
pubmed-meshheading:19798642-Brain,
pubmed-meshheading:19798642-Diagnosis, Differential,
pubmed-meshheading:19798642-Female,
pubmed-meshheading:19798642-Follow-Up Studies,
pubmed-meshheading:19798642-Humans,
pubmed-meshheading:19798642-Image Enhancement,
pubmed-meshheading:19798642-Magnetic Resonance Imaging,
pubmed-meshheading:19798642-Male,
pubmed-meshheading:19798642-Multiple Sclerosis,
pubmed-meshheading:19798642-Neuromyelitis Optica
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pubmed:year |
2009
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pubmed:articleTitle |
"Cloud-like enhancement" is a magnetic resonance imaging abnormality specific to neuromyelitis optica.
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pubmed:affiliation |
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan. sito@faculty.chiba-u.jp
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pubmed:publicationType |
Journal Article,
Comparative Study
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