Linked Life Data

19796661

Source:http://linkedlifedata.com/resource/pubmed/id/19796661

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2009-11-20
pubmed:abstractText
Molecular imaging has the potential to transform the field of diagnostic imaging through enabling far more detailed investigation and characterisation of disease processes than is currently possible. Magnetic resonance imaging (MRI) is capable of three-dimensional non-invasive imaging of opaque tissues at near cellular resolution. Among the imaging techniques available today, MRI has, perhaps, the greatest potential to exploit the possibilities that molecular imaging presents. Nanoparticles are the focus of intense research, due to a wide variety of potential applications in the biomedical, optical, and electronic fields. In this article we examine the progress made in the development of nanoparticles as targeted contrast agents for molecular magnetic resonance imaging. In particular, we will examine the potential of antibody-targeted liposomes (immunoliposomes) as vehicles for delivering MRI contrast agents to cellular biomarkers, thus enabling visualisation of structures and processes at the molecular level. We will address some of the challenges that must be faced by researchers in this field before the progress made in the laboratory can be translated into improved clinical diagnostics and therapeutics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1872-8294
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1402-11
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Molecular and magnetic resonance imaging: The value of immunoliposomes.
pubmed:affiliation
School of Biotechnology and National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland. dorotakozlowska2@gmail.com
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't