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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-10-1
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pubmed:abstractText |
Breast cancer is a heterogeneous disease that is not totally eradicated by current therapies. The classification of breast tumors into distinct molecular subtypes by gene profiling and immunodetection of surrogate markers has proven useful for tumor prognosis and prediction of effective targeted treatments. The challenge now is to identify molecular biomarkers that may be of functional relevance for personalized therapy of breast tumors with poor outcome that do not respond to available treatments. The Mitochondrial Tumor Suppressor (MTUS1) gene is an interesting candidate whose expression is reduced in colon, pancreas, ovary and oral cancers. The present study investigates the expression and functional effects of MTUS1 gene products in breast cancer.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AndréNicolasN,
pubmed-author:CazaubonSylvieS,
pubmed-author:ChaverotNathalieN,
pubmed-author:ColassonHélèneH,
pubmed-author:DelattreOlivierO,
pubmed-author:Di TommasoAnneA,
pubmed-author:DimitrovArianeA,
pubmed-author:GruelNadègeN,
pubmed-author:MoliniéVincentV,
pubmed-author:NahmiasClaraC,
pubmed-author:PerezFranckF,
pubmed-author:RadvanyiFrançoisF,
pubmed-author:ReyalFabienF,
pubmed-author:Rodrigues-FerreiraSylvieS,
pubmed-author:Sigal-ZafraniBrigitteB,
pubmed-author:TerrisBenoitB,
pubmed-author:Vincent-SalomonAnneA
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e7239
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pubmed:meshHeading |
pubmed-meshheading:19794912-Humans,
pubmed-meshheading:19794912-Animals,
pubmed-meshheading:19794912-Mice,
pubmed-meshheading:19794912-Breast Neoplasms,
pubmed-meshheading:19794912-Prognosis,
pubmed-meshheading:19794912-Female,
pubmed-meshheading:19794912-Carcinoma,
pubmed-meshheading:19794912-Mitosis,
pubmed-meshheading:19794912-Neoplasm Invasiveness,
pubmed-meshheading:19794912-Chromosome Mapping,
pubmed-meshheading:19794912-HeLa Cells,
pubmed-meshheading:19794912-Carrier Proteins,
pubmed-meshheading:19794912-Cell Proliferation,
pubmed-meshheading:19794912-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19794912-Chromosomes, Human, Pair 8,
pubmed-meshheading:19794912-Tumor Suppressor Proteins,
pubmed-meshheading:19794912-Mice, SCID
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