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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-2-8
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pubmed:abstractText |
Occult hepatitis B infection (OBI) is characterized as a form of hepatitis in which, despite the absence of detectable hepatitis B surface antigen (HBsAg), hepatitis B virus DNA (HBV-DNA) is present in a patient's peripheral blood. Investigators believe that divergent genetics and immunological parameters vary between resistant individuals and patients with OBI. Vitamin D3 and its known receptor appear to be involved in antiviral immune responses. Therefore, because OBI is a form of viral infection, the aim of this study was to investigate the association between polymorphisms in intron 8 and exon 9 of the vitamin D receptor (VDR) with OBI.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1440-1746
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
90-3
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pubmed:meshHeading |
pubmed-meshheading:19793172-Adult,
pubmed-meshheading:19793172-Asian Continental Ancestry Group,
pubmed-meshheading:19793172-Case-Control Studies,
pubmed-meshheading:19793172-DNA, Viral,
pubmed-meshheading:19793172-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19793172-Exons,
pubmed-meshheading:19793172-Female,
pubmed-meshheading:19793172-Genetic Predisposition to Disease,
pubmed-meshheading:19793172-Hepatitis B,
pubmed-meshheading:19793172-Hepatitis B Antibodies,
pubmed-meshheading:19793172-Hepatitis B Surface Antigens,
pubmed-meshheading:19793172-Hepatitis B virus,
pubmed-meshheading:19793172-Humans,
pubmed-meshheading:19793172-Introns,
pubmed-meshheading:19793172-Iran,
pubmed-meshheading:19793172-Male,
pubmed-meshheading:19793172-Middle Aged,
pubmed-meshheading:19793172-Phenotype,
pubmed-meshheading:19793172-Polymerase Chain Reaction,
pubmed-meshheading:19793172-Polymorphism, Genetic,
pubmed-meshheading:19793172-Receptors, Calcitriol
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pubmed:year |
2010
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pubmed:articleTitle |
Association of exon 9 but not intron 8 VDR polymorphisms with occult HBV infection in south-eastern Iranian patients.
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pubmed:affiliation |
Department of Immunology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
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pubmed:publicationType |
Journal Article
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