19789302

Source:http://linkedlifedata.com/resource/pubmed/id/19789302

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0009404, umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0054874, umls-concept:C0302600, umls-concept:C1269955, umls-concept:C1533157
pubmed:issue	19
pubmed:dateCreated	2009-10-2
pubmed:abstractText	Cathepsin S is a cysteine protease that promotes the invasion of tumor and endothelial cells during cancer progression. Here we investigated the potential to target cathepsin S using an antagonistic antibody, Fsn0503, to block these tumorigenic effects.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Cathepsins, http://linkedlifedata.com/resource/pubmed/chemical/cathepsin S
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1078-0432
pubmed:author	pubmed-author:BurdenRoberta ERE, pubmed-author:GormleyJulie AJA, pubmed-author:HegartyShauna MSM, pubmed-author:JaquinThomas JTJ, pubmed-author:JohnstonJames AJA, pubmed-author:OlwillShane ASA, pubmed-author:QuinnDerek JDJ, pubmed-author:ScottChristopher JCJ, pubmed-author:SmallDonna MDM, pubmed-author:WalkerBrianB, pubmed-author:WardClaireC
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	6042-51
pubmed:meshHeading	pubmed-meshheading:19789302-Adenocarcinoma, pubmed-meshheading:19789302-Animals, pubmed-meshheading:19789302-Antibodies, Monoclonal, pubmed-meshheading:19789302-Antineoplastic Agents, pubmed-meshheading:19789302-Cathepsins, pubmed-meshheading:19789302-Cell Movement, pubmed-meshheading:19789302-Cells, Cultured, pubmed-meshheading:19789302-Colorectal Neoplasms, pubmed-meshheading:19789302-Female, pubmed-meshheading:19789302-HCT116 Cells, pubmed-meshheading:19789302-Humans, pubmed-meshheading:19789302-Immunotherapy, pubmed-meshheading:19789302-Mice, pubmed-meshheading:19789302-Mice, Inbred BALB C, pubmed-meshheading:19789302-Mice, Nude, pubmed-meshheading:19789302-Neoplasm Invasiveness, pubmed-meshheading:19789302-Neovascularization, Pathologic, pubmed-meshheading:19789302-Rats, pubmed-meshheading:19789302-Rats, Wistar, pubmed-meshheading:19789302-Xenograft Model Antitumor Assays
pubmed:year	2009
pubmed:articleTitle	Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis.
pubmed:affiliation	School of Pharmacy, Queen's University Belfast, Belfast, United Kingdom.
pubmed:publicationType	Journal Article