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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
15
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pubmed:dateCreated |
2009-10-13
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|
pubmed:abstractText |
Aging is a major risk factor for the development of atherosclerosis and coronary artery disease. Through a microarray approach, we have identified a microRNA (miR-217) that is progressively expressed in endothelial cells with aging. miR-217 regulates the expression of silent information regulator 1 (SirT1), a major regulator of longevity and metabolic disorders that is progressively reduced in multiple tissues during aging.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
pubmed-author:AmatiFrancescaF,
pubmed-author:CardelliniMarinaM,
pubmed-author:CasagrandeVivianaV,
pubmed-author:FedericiMassimoM,
pubmed-author:IppolitiArnaldoA,
pubmed-author:LauroRenatoR,
pubmed-author:MartelliEugenioE,
pubmed-author:MelinoGerryG,
pubmed-author:MenghiniRossellaR,
pubmed-author:NovelliGiuseppeG,
pubmed-author:TerrinoniAlessandroA,
pubmed-author:Vasa-NicoteraMariucaM
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|
pubmed:issnType |
Electronic
|
|
pubmed:day |
13
|
|
pubmed:volume |
120
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1524-32
|
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.
|
|
pubmed:affiliation |
Department of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
