|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2010-1-21
|
|
pubmed:abstractText |
Insulin-like growth factor 1 (IGF1) is a peptide growth factor that promotes cell proliferation and inhibits apoptosis. The bioavailability of IGF1 is regulated by the insulin-like growth factor binding protein 3 (IGFBP3). The purpose of this study was to examine the association of genetic variants in IGF1 (rs6214, rs6220, and rs35767) and IGFBP3 (rs2854744 and rs2854746) with risk of colorectal polyps and colorectal cancer.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1573-7225
|
|
pubmed:author |
pubmed-author:BaierlAndreasA,
pubmed-author:FührlingerGerhardG,
pubmed-author:FeikElisabethE,
pubmed-author:GsurAndreaA,
pubmed-author:HiegerBarbaraB,
pubmed-author:LeebGernotG,
pubmed-author:MachKarlK,
pubmed-author:MickscheMichaelM,
pubmed-author:PentzAstridA,
pubmed-author:PulgramThomasT,
pubmed-author:StättnerStefanS,
pubmed-author:WeissWernerW
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
21
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
91-7
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:19784788-Aged,
pubmed-meshheading:19784788-Aged, 80 and over,
pubmed-meshheading:19784788-Colonic Polyps,
pubmed-meshheading:19784788-Colorectal Neoplasms,
pubmed-meshheading:19784788-Female,
pubmed-meshheading:19784788-Genetic Predisposition to Disease,
pubmed-meshheading:19784788-Humans,
pubmed-meshheading:19784788-Insulin-Like Growth Factor Binding Protein 3,
pubmed-meshheading:19784788-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:19784788-Insulin-Like Growth Factor I,
pubmed-meshheading:19784788-Logistic Models,
pubmed-meshheading:19784788-Male,
pubmed-meshheading:19784788-Middle Aged,
pubmed-meshheading:19784788-Polymorphism, Genetic,
pubmed-meshheading:19784788-Risk Factors
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk.
|
|
pubmed:affiliation |
Department of Medicine I, Institute of Cancer Research, Medical University of Vienna,Vienna, Austria.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
