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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
1990-12-21
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pubmed:abstractText |
Optimal conditions for the assessment of T cell proliferation and cytolytic T lymphocyte (CTL) responses specific for primate lentivirus were established. CTL and T cell proliferative responses were demonstrated as early as two weeks post-infection. Although the majority of CTL were CD8+, MHC class I-restricted, this study demonstrated CD4+, MHC class II-restricted CTL. Experiments also demonstrated that CTL were CD16 negative. Target cell generation could be blocked with CD4 mAb specific for the SIV binding site.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0047-2565
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-87
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1977918-Animals,
pubmed-meshheading:1977918-Antibodies, Viral,
pubmed-meshheading:1977918-Blotting, Western,
pubmed-meshheading:1977918-CD4-Positive T-Lymphocytes,
pubmed-meshheading:1977918-Cell Division,
pubmed-meshheading:1977918-Female,
pubmed-meshheading:1977918-Histocompatibility Antigens Class II,
pubmed-meshheading:1977918-Macaca mulatta,
pubmed-meshheading:1977918-Male,
pubmed-meshheading:1977918-Phenotype,
pubmed-meshheading:1977918-Simian Acquired Immunodeficiency Syndrome,
pubmed-meshheading:1977918-Simian immunodeficiency virus,
pubmed-meshheading:1977918-T-Lymphocytes,
pubmed-meshheading:1977918-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:1977918-T-Lymphocytes, Regulatory
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pubmed:year |
1990
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pubmed:articleTitle |
Cellular immune response of SIV-infected rhesus macaques.
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pubmed:affiliation |
Department of Medical Pathology, University of California, Davis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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