Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-2-1
pubmed:abstractText
Despite much progress in prostate cancer management, new diagnostic, prognostic and therapeutic tools are needed to predict disease severity, choose among the available treatments and establish more effective therapies for advanced prostate cancer. In the last few years, compelling evidence has documented the role of microRNAs as new broad-spectrum oncogenes or tumour suppressor genes, thus their use as diagnostic, prognostic and therapeutic biomolecules is envisaged. This review extensively and critically summarizes the current knowledge about microRNA deregulation in prostate cancer disease, underlining present limits and future perspectives.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1479-6821
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
F1-17
pubmed:meshHeading
pubmed-meshheading:19779034-Adenocarcinoma, pubmed-meshheading:19779034-Androgens, pubmed-meshheading:19779034-Cell Transformation, Neoplastic, pubmed-meshheading:19779034-Disease Progression, pubmed-meshheading:19779034-Gene Expression Profiling, pubmed-meshheading:19779034-Gene Expression Regulation, Neoplastic, pubmed-meshheading:19779034-Genes, Tumor Suppressor, pubmed-meshheading:19779034-Humans, pubmed-meshheading:19779034-Male, pubmed-meshheading:19779034-MicroRNAs, pubmed-meshheading:19779034-Neoplasm Invasiveness, pubmed-meshheading:19779034-Neoplasm Proteins, pubmed-meshheading:19779034-Neoplasms, Hormone-Dependent, pubmed-meshheading:19779034-Prognosis, pubmed-meshheading:19779034-Prostatic Neoplasms, pubmed-meshheading:19779034-Proto-Oncogene Proteins c-myc, pubmed-meshheading:19779034-RNA, Neoplasm
pubmed:year
2010
pubmed:articleTitle
MicroRNAs and prostate cancer.
pubmed:affiliation
Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore Sanità, viale Regina Elena 299, 00161 Rome, Italy. valeria.coppola@iss.it
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't