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rdf:type |
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lifeskim:mentions |
umls-concept:C0012155,
umls-concept:C0022646,
umls-concept:C0026809,
umls-concept:C0205263,
umls-concept:C0333516,
umls-concept:C1332322,
umls-concept:C1420814,
umls-concept:C1762617,
umls-concept:C1801960,
umls-concept:C1883709,
umls-concept:C2349975
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pubmed:issue |
12
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pubmed:dateCreated |
2009-11-20
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pubmed:abstractText |
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily of cytokines. TWEAK binds and activates the Fn14 receptor, and may regulate apoptosis, inflammation, and angiogenesis, in different pathological conditions. We have evaluated the effect of exogenous TWEAK administration as well as the role of endogenous TWEAK on proinflammatory cytokine expression and vascular and renal injury severity in hyperlipidemic ApoE-knockout mice.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/TNFSF12 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf12 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factors,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:Blanco-ColioLuis MiguelLM,
pubmed-author:BlancoJuliaJ,
pubmed-author:BurklyLinda CLC,
pubmed-author:EgidoJesúsJ,
pubmed-author:JakubowskiAnielaA,
pubmed-author:López-FrancoOscarO,
pubmed-author:Martín-VenturaJosé LuisJL,
pubmed-author:MorenoJuan AntonioJA,
pubmed-author:Muñoz-GarcíaBegoñaB,
pubmed-author:OrtizAlbertoA,
pubmed-author:SanzAna BelénAB
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2061-8
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pubmed:meshHeading |
pubmed-meshheading:19778942-Animals,
pubmed-meshheading:19778942-Antibodies, Monoclonal,
pubmed-meshheading:19778942-Apolipoproteins E,
pubmed-meshheading:19778942-Atherosclerosis,
pubmed-meshheading:19778942-Blood Vessels,
pubmed-meshheading:19778942-Cytokines,
pubmed-meshheading:19778942-Diet, Atherogenic,
pubmed-meshheading:19778942-Gene Expression,
pubmed-meshheading:19778942-Humans,
pubmed-meshheading:19778942-Hyperlipidemias,
pubmed-meshheading:19778942-Inflammation Mediators,
pubmed-meshheading:19778942-Kidney,
pubmed-meshheading:19778942-Lipoproteins, LDL,
pubmed-meshheading:19778942-Macrophages,
pubmed-meshheading:19778942-Male,
pubmed-meshheading:19778942-Mice,
pubmed-meshheading:19778942-Mice, Knockout,
pubmed-meshheading:19778942-NF-kappa B,
pubmed-meshheading:19778942-Recombinant Proteins,
pubmed-meshheading:19778942-Tumor Necrosis Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice.
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pubmed:affiliation |
Vascular Research Laboratory, Fundación Jiménez Díaz, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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