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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1990-12-5
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pubmed:abstractText |
Intestinal secretion is enhanced by starvation in rats. The rectum from fed and 3-day-starved rats generates a basal electrogenic ion transfer (short-circuit current) in vitro which is mainly electrogenic Na+ absorption (amiloride-sensitive, 66-71%) with a small component of electrogenic chloride secretion (furosemide-sensitive, 14-22%). Bethanechol, a muscarinic agonist, caused an increase in the short-circuit current (mainly furosemide-sensitive chloride secretion) and potential difference in rectums from both fed and starved rats but the respective values for the starved animals were 100% and 64% greater. In starvation, the rat rectum is an indicator of intestinal secretory status. The result warrants investigation of human rectal electrogenic secretion in nutritional deprivation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amiloride,
http://linkedlifedata.com/resource/pubmed/chemical/Bethanechol,
http://linkedlifedata.com/resource/pubmed/chemical/Bethanechol Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorides,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0958-0670
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
609-11
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1977420-Absorption,
pubmed-meshheading:1977420-Amiloride,
pubmed-meshheading:1977420-Animals,
pubmed-meshheading:1977420-Bethanechol,
pubmed-meshheading:1977420-Bethanechol Compounds,
pubmed-meshheading:1977420-Chlorides,
pubmed-meshheading:1977420-Electrophysiology,
pubmed-meshheading:1977420-Intestinal Secretions,
pubmed-meshheading:1977420-Male,
pubmed-meshheading:1977420-Rats,
pubmed-meshheading:1977420-Rectum,
pubmed-meshheading:1977420-Sodium,
pubmed-meshheading:1977420-Starvation
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pubmed:year |
1990
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pubmed:articleTitle |
Rectal electrogenic secretion--is it a putative indicator of intestinal secretory status induced by nutritional deprivation in the rat?
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pubmed:affiliation |
Department of Biomedical Science, University of Sheffield.
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pubmed:publicationType |
Journal Article
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