Linked Life Data

19772873

Source:http://linkedlifedata.com/resource/pubmed/id/19772873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-11-13
pubmed:abstractText
Abnormalities in neonatal sensory evoked potentials (EPs) may indicate a poor developmental prognosis, but such EPs are highly variable, changing with development, and requiring subjective analysis. 'Weight of Evidence' (W), the logarithm of the ratio of the probability that a response has occurred to the probability that it has not, and 'Response Entropy' (S), the spread of the response over time and frequency bands, might provide objective and quantitative measures of EP abnormalities and developmental changes, based on information processing characteristics. W and S were calculated from visual and somatosensory EPs recorded in 72 premature newborns over 2 sessions, separated by 6-9 weeks. Group 1 had normal brain ultrasound images at the time of recording, and a normal developmental outcome at age 2 years. Group 2 had abnormal brain ultrasound images but normal outcome. Group 3 had abnormal brain imaging and abnormal outcome.W values were lowest in Group 3 (visual p<0.001: somatosensory p<0.04). Entropy diminished between sessions (visual p<0.001: somatosensory p<0.015): it was highest in Group 2 (visual p<0.03). The low W in Group 3 implies a lower signal/noise ratio, reducing information capacity. Decreasing entropy suggests more efficient information encoding with maturation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1872-678X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
185
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-107
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
'Weight of Evidence' analysis of neonatal sensory evoked potentials.
pubmed:affiliation
Centre for Child and Adolescent Health, University of Bristol, Bristol, UK. Oliver.Stanley@uhbristol.nhs.uk
pubmed:publicationType
Journal Article