Linked Life Data

1977198

Source:http://linkedlifedata.com/resource/pubmed/id/1977198

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
39
pubmed:dateCreated
1990-11-15
pubmed:abstractText
The serum concentration of gamma-glutamyltransferase (gamma-GT) was serially measured in 26 cancer patients undergoing chemotherapy for liver metastases. 20 patients were studied retrospectively and 6 prospectively with emphasis on the first few days of cytostatic treatment. The gamma-GT determinations during the first days of treatment gave no indication of the prognosis of remission. Serial measurements during treatment do, however, serve to objectify the success of the chemotherapy. In most patients the gamma-GT concentrations paralleled the general condition as well as palpation and ultrasound examination of the liver. Direct interactions of cytotoxic drugs with gamma-GT could not be demonstrated. gamma-GT determinations are therefore of help in phase II studies in evaluating new drugs for their cytostatic activity against liver metastases.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-7672
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1435-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[The significance of gamma-glutamyltransferase in the evaluation of the results of chemotherapy of liver metastasis].
pubmed:affiliation
Departement für Innere Medizin, Universitätsspital Zürich.
pubmed:publicationType
Journal Article, English Abstract