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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2009-10-6
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pubmed:abstractText |
Shortening of mean telomere length (TL) in white blood cells is correlated with the development of coronary heart disease (CHD) and with increased mortality due to infectious disease. The goal of the present study was to investigate whether telomere shortening in CHD is restricted to specific peripheral blood lymphocyte and/or myeloid cell subpopulations. Results were correlated to TL in CD34+ hematopoietic peripheral blood stem cells and progenitor cells obtained from the same individual patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
6
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1364-72
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pubmed:meshHeading |
pubmed-meshheading:19770396-Adult,
pubmed-meshheading:19770396-Aged,
pubmed-meshheading:19770396-CD8-Positive T-Lymphocytes,
pubmed-meshheading:19770396-Coronary Disease,
pubmed-meshheading:19770396-Cytomegalovirus,
pubmed-meshheading:19770396-Cytomegalovirus Infections,
pubmed-meshheading:19770396-Flow Cytometry,
pubmed-meshheading:19770396-Granulocytes,
pubmed-meshheading:19770396-Humans,
pubmed-meshheading:19770396-In Situ Hybridization, Fluorescence,
pubmed-meshheading:19770396-Inflammation,
pubmed-meshheading:19770396-Leukocytes,
pubmed-meshheading:19770396-Male,
pubmed-meshheading:19770396-Middle Aged,
pubmed-meshheading:19770396-Monocytes,
pubmed-meshheading:19770396-Myocardial Infarction,
pubmed-meshheading:19770396-Reference Values,
pubmed-meshheading:19770396-Telomerase,
pubmed-meshheading:19770396-Telomere,
pubmed-meshheading:19770396-Ventricular Dysfunction, Left
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pubmed:year |
2009
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pubmed:articleTitle |
Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.
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pubmed:affiliation |
Institute of Human Genetics, Newcastle University, International Centre for Life, Central Parkway, Newcastle Upon Tyne NE13BZ, United Kingdom. ioakim.spyridopoulos@newcastle.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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