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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-9-30
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pubmed:abstractText |
Children with airway malacia often have protracted courses of airway infections, because dynamic airway collapse during coughing results in impaired mucociliary clearance. The aim of this study was to determine the effect of the mucolytic drug recombinant human deoxyribonuclease (rhDNase) on the recovery of respiratory symptoms in children with airway malacia and lower respiratory tract infection (LRTI).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1099-0496
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
962-9
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pubmed:meshHeading |
pubmed-meshheading:19768804-Administration, Inhalation,
pubmed-meshheading:19768804-Adolescent,
pubmed-meshheading:19768804-Airway Obstruction,
pubmed-meshheading:19768804-Bronchomalacia,
pubmed-meshheading:19768804-Child,
pubmed-meshheading:19768804-Child, Preschool,
pubmed-meshheading:19768804-Deoxyribonuclease I,
pubmed-meshheading:19768804-Dose-Response Relationship, Drug,
pubmed-meshheading:19768804-Double-Blind Method,
pubmed-meshheading:19768804-Drug Administration Schedule,
pubmed-meshheading:19768804-Female,
pubmed-meshheading:19768804-Follow-Up Studies,
pubmed-meshheading:19768804-Forced Expiratory Volume,
pubmed-meshheading:19768804-Humans,
pubmed-meshheading:19768804-Male,
pubmed-meshheading:19768804-Multivariate Analysis,
pubmed-meshheading:19768804-Pneumonia,
pubmed-meshheading:19768804-Probability,
pubmed-meshheading:19768804-Prospective Studies,
pubmed-meshheading:19768804-Recombinant Proteins,
pubmed-meshheading:19768804-Respiratory Function Tests,
pubmed-meshheading:19768804-Respiratory Tract Infections,
pubmed-meshheading:19768804-Risk Assessment,
pubmed-meshheading:19768804-Severity of Illness Index,
pubmed-meshheading:19768804-Statistics, Nonparametric,
pubmed-meshheading:19768804-Treatment Outcome,
pubmed-meshheading:19768804-Vital Capacity
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pubmed:year |
2009
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pubmed:articleTitle |
Recombinant human DNase in children with airway malacia and lower respiratory tract infection.
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pubmed:affiliation |
Division of Pulmonology, Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Erasmus University Medical Centre, Rotterdam, The Netherlands. r.boogaard@erasmusmc.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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