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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-11-16
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pubmed:abstractText |
A Helicobacter pylori mutant defective in a putative mfd gene was constructed and characterized. The mfd gene is required for DNA repair and is involved in DNA recombination processes. The mfd mutant strain displayed a greatly increased susceptibility to antibiotics, indicating that this gene plays a significant role in the antibiotic resistance of H. pylori strain J99.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1879-0070
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
454-6
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pubmed:meshHeading |
pubmed-meshheading:19766427-Anti-Bacterial Agents,
pubmed-meshheading:19766427-Bacterial Proteins,
pubmed-meshheading:19766427-Colony Count, Microbial,
pubmed-meshheading:19766427-DNA Repair,
pubmed-meshheading:19766427-Drug Resistance, Bacterial,
pubmed-meshheading:19766427-Gene Deletion,
pubmed-meshheading:19766427-Helicobacter pylori,
pubmed-meshheading:19766427-Microbial Sensitivity Tests,
pubmed-meshheading:19766427-Mitomycin,
pubmed-meshheading:19766427-Recombination, Genetic,
pubmed-meshheading:19766427-Transcription Factors
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pubmed:year |
2009
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pubmed:articleTitle |
The Helicobacter pylori Mfd protein is important for antibiotic resistance and DNA repair.
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|
pubmed:affiliation |
Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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