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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-12-7
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pubmed:abstractText |
Research suggests that individuals who start drinking at an early age are more likely to subsequently develop alcohol dependence. Twin studies have demonstrated that the liability to age at first drink and to alcohol dependence are influenced by common genetic and environmental factors, however, age at first drink may also environmentally mediate increased risk for alcohol dependence. In this study, we examine whether age at first drink moderates genetic and environmental influences, via gene x environment interactions, on DSM-IV alcohol dependence symptoms.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1530-0277
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pubmed:author |
pubmed-author:AgrawalArpanaA,
pubmed-author:BucholzKathleen KKK,
pubmed-author:GrantJulia DJD,
pubmed-author:GruczaRichardR,
pubmed-author:HeathAndrew CAC,
pubmed-author:LynskeyMichael TMT,
pubmed-author:MaddenPamela A FPA,
pubmed-author:MartinNicholas GNG,
pubmed-author:NelsonElliot CEC,
pubmed-author:PergadiaMichele LML,
pubmed-author:SartorCarolyn ECE
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2047-56
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pubmed:dateRevised |
2011-3-3
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pubmed:meshHeading |
pubmed-meshheading:19764935-Adult,
pubmed-meshheading:19764935-Age of Onset,
pubmed-meshheading:19764935-Alcohol Drinking,
pubmed-meshheading:19764935-Alcoholism,
pubmed-meshheading:19764935-Australia,
pubmed-meshheading:19764935-Female,
pubmed-meshheading:19764935-Genetic Predisposition to Disease,
pubmed-meshheading:19764935-Humans,
pubmed-meshheading:19764935-Individuality,
pubmed-meshheading:19764935-Male,
pubmed-meshheading:19764935-Models, Genetic,
pubmed-meshheading:19764935-Psychiatric Status Rating Scales,
pubmed-meshheading:19764935-Risk Factors,
pubmed-meshheading:19764935-Social Environment,
pubmed-meshheading:19764935-Survival Analysis,
pubmed-meshheading:19764935-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms.
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pubmed:affiliation |
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO 63110, USA. arpana@wustl.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Twin Study
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