Linked Life Data

19762013

Source:http://linkedlifedata.com/resource/pubmed/id/19762013

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-12-6
pubmed:abstractText
Neuropsychological and neurophysiological studies have suggested that prefrontal cortex may be involved in non-verbal number processing, when relevant for current behavioural goals. More precisely, it has been suggested that an intact right inferior frontal gyrus (rIFG) in humans may be necessary to the use of a spatial representation of numbers, also known as mental number line. In a popular model of spatial functions (e.g., Corbetta et al., 2008), rIFG is part of a right-lateralised ventral fronto-parietal network that conveys signals to a dorsal network supporting attentional orienting in contralateral space. Within the dorsal network, the frontal eye fields (FEF) are known to contribute to visual scene analysis and visual conjunction search tasks when eye movement commands are not required. In the present study, we hypothesised they might also be involved in exploring a conceptual space, such as the mental number line. We examined the proposed functions of the human rIFG and right Frontal Eye Field (rFEF) by interfering with their normal functioning with repetitive Transcranial Magnetic Stimulation (rTMS) while participants performed numerical tasks. The results suggest that, when number magnitude is relevant to the task, rIFG supports orienting to the entire mental number line while rFEF are crucial for contralateral orienting (that is towards small numbers).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1973-8102
pubmed:author
pubmed:copyrightInfo
Copyright © 2009 Elsevier Srl. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2-13
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Contribution of frontal cortex to the spatial representation of number.
pubmed:affiliation
Institute of Cognitive Neuroscience, University College London, UK. e.rusconi@ucl.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't