Linked Life Data

19760769

Source:http://linkedlifedata.com/resource/pubmed/id/19760769

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:19760769rdf:typepubmed:Citationlld:pubmed
pubmed-article:19760769lifeskim:mentionsumls-concept:C0249880lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0333875lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C1510965lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0079104lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C1707455lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0237881lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0242349lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0750502lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C1524063lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0205258lld:lifeskim
pubmed-article:19760769lifeskim:mentionsumls-concept:C0332147lld:lifeskim
pubmed-article:19760769pubmed:issue3lld:pubmed
pubmed-article:19760769pubmed:dateCreated2010-2-10lld:pubmed
pubmed-article:19760769pubmed:abstractTextEven though p16(INK4a) (p16) immunocytochemistry has proven a useful accessory tool verifying the identification of atypical squamous cells of undetermined significance (ASC-US) categorized smears, the procedure still has limitations. To date few studies examining the usefulness of p16 immunocytochemistry in atypical squamous cells which cannot exclude HSIL (ASC-H), compared with ASC-US in liquid-based cervical smears. Therefore, we examined the correlation of p16 immunocytochemical staining with follow-up biopsy results on ASC-H categorized smears and compared the data with those classified as ASC-US on 105 liquid-based cytology samples. We found no statistical significance in the p16 expression of ASC-US smears and the presence of squamous intraepithelial lesions (SIL) in follow-up biopsies (p = 0.546). However, p16 expression did significantly correlate with the presence of SIL (p = 0.002) in ASC-H smears. There was a statistically significant relationship between p16 expression and presence of high grade squamous intraepithelial lesions (HSIL) or more on the follow-up biopsies in both ASC-US (p = 0.012) and ASC-H (p < 0.001) categorized smears. In ASC-US categorized smears, there was no statistical significance between p16 expression and the HR-HPV viral load (p = 0.091). But there was a statistical significance between p16 expression and the HR-HPV viral load (p < 0.001) in ASC-H categorized smears. Our results indicate that p16 immunostaining is a much better useful marker for HR-HPV infection and detection of SIL in ASC-H categorized smears compared to those defined as ASC-US.lld:pubmed
pubmed-article:19760769pubmed:languageenglld:pubmed
pubmed-article:19760769pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19760769pubmed:citationSubsetIMlld:pubmed
pubmed-article:19760769pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19760769pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19760769pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19760769pubmed:statusMEDLINElld:pubmed
pubmed-article:19760769pubmed:monthMarlld:pubmed
pubmed-article:19760769pubmed:issn1097-0339lld:pubmed
pubmed-article:19760769pubmed:authorpubmed-author:OhYoung...lld:pubmed
pubmed-article:19760769pubmed:authorpubmed-author:SongSang...lld:pubmed
pubmed-article:19760769pubmed:authorpubmed-author:SungChang...lld:pubmed
pubmed-article:19760769pubmed:authorpubmed-author:KimSeong...lld:pubmed
pubmed-article:19760769pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19760769pubmed:volume38lld:pubmed
pubmed-article:19760769pubmed:ownerNLMlld:pubmed
pubmed-article:19760769pubmed:authorsCompleteYlld:pubmed
pubmed-article:19760769pubmed:pagination168-71lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:meshHeadingpubmed-meshheading:19760769...lld:pubmed
pubmed-article:19760769pubmed:year2010lld:pubmed
pubmed-article:19760769pubmed:articleTitleThe use of p16(INK4A) immunocytochemistry in "Atypical squamous cells which cannot exclude HSIL" compared with "Atypical squamous cells of undetermined significance" in liquid-based cervical smears.lld:pubmed
pubmed-article:19760769pubmed:affiliationDepartment of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.lld:pubmed
pubmed-article:19760769pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19760769pubmed:publicationTypeComparative Studylld:pubmed