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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-12-29
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pubmed:abstractText |
We examined (1) the association of SLC6A4 genotypes and alcohol dependence (AD) in a sample of alcoholics; (2) the validity of lifetime occurrence of blacked-out violent impulsive behaviour (BOVIB) during binge drinking bouts as a criterion for subtyping AD patients and (3) a mechanistic hypothesis for BOVIB involving tryptophan-2,3-dioxygenase (TDO) activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1464-3502
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-88
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pubmed:meshHeading |
pubmed-meshheading:19759277-Administration, Oral,
pubmed-meshheading:19759277-Adolescent,
pubmed-meshheading:19759277-Adult,
pubmed-meshheading:19759277-Alcoholism,
pubmed-meshheading:19759277-Amnesia,
pubmed-meshheading:19759277-Female,
pubmed-meshheading:19759277-Genetic Predisposition to Disease,
pubmed-meshheading:19759277-Genotype,
pubmed-meshheading:19759277-Humans,
pubmed-meshheading:19759277-Impulsive Behavior,
pubmed-meshheading:19759277-Kynurenine,
pubmed-meshheading:19759277-Middle Aged,
pubmed-meshheading:19759277-Polymorphism, Genetic,
pubmed-meshheading:19759277-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:19759277-Tryptophan,
pubmed-meshheading:19759277-Tryptophan Oxygenase,
pubmed-meshheading:19759277-Violence
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pubmed:articleTitle |
Impact of tryptophan metabolism on the vulnerability to alcohol-related blackouts and violent impulsive behaviours.
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pubmed:affiliation |
Centre Hospitalier Universitaire, Service d'Addictologie, 59037 Lille Cedex, France. j-vignau@chru-lille.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Validation Studies
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